Worldwide, there are plants known as psychoactive plants that naturally contain psychedelic active components. They have a high concentration of neuroprotective substances that can interact with the nervous system to produce psychedelic effects. Despite these plants' hazardous potential, recreational use of them is on the rise because of their psychoactive properties. Early neuroscience studies relied heavily on psychoactive plants and plant natural products (NPs), and both recreational and hazardous NPs have contributed significantly to the understanding of almost all neurotransmitter systems. Worldwide, there are many plants that contain psychoactive properties, and people have been using them for ages. Psychoactive plant compounds may significantly alter how people perceive the world.
1. Sci Rep. 2016 Nov 14;6:36752. doi: 10.1038/srep36752. Rhodomollins A and B, two Diterpenoids with an Unprecedented Backbone from the Fruits of Rhododendron molle. Li Y(1), Liu YB(1), Yan HM(1), Liu YL(1), Li YH(2), Lv HN(1), Ma SG(1), Qu J(1), Yu SS(1). Author information: (1)State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union, Medical College, Beijing 100050, People's Republic of China. (2)Institute of Medicinal, Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical, College, Beijing 100050, People's Republic of China. Two new grayanoids, rhodomollin A (1) and rhodomollin B (2), possessing an unprecedented D-homo grayanane carbon skeleton, were isolated from the fruits of Rhododendron molle. The structures of 1 and 2 were fully characterized using a combination of spectroscopic analyses and X-ray crystallography. Rhodomollin B (2) exhibited modest activity against influenza virus A/95-359, with an IC50 value of 19.24 μM. DOI: 10.1038/srep36752 PMCID: PMC5107939 PMID: 27841292 [Indexed for MEDLINE]