Psychoactive Plant Database - Neuroactive Phytochemical Collection

1. J Environ Manage. 2023 Oct 28;349:119429. doi: 10.1016/j.jenvman.2023.119429. 
Online ahead of print.

Combination of coagulation and adsorption technologies for advanced wastewater 
treatment for potable water reuse: By ANN, NSGA-II, and RSM.

Zahmatkesh S(1), Karimian M(2), Chen Z(3), Ni BJ(4).

Author information:
(1)Tecnologico de Monterrey, Escuela de Ingenieríay Ciencias, Puebla, Mexico; 
Faculty of Health and Life Sciences, INTI International University, 71800, 
Nilai, Negeri Sembilan, Malaysia.
(2)Faculty of Civil Engineering, Architecture and Urban Planning, University of 
Eyvanekey, Iran.
(3)Centre for Technology in Water and Wastewater, School of Civil and 
Environmental Engineering, University of Technology Sydney, Sydney, NSW, 2007, 
Australia.
(4)School of Civil and Environmental Engineering, The University of New South 
Wales, Sydney, NSW, 2052, Australia. Electronic address: bingjieni@gmail.com.

To reuse water and reduce water pollution, such as chemical oxygen demand (COD), 
total suspended solids (TSS), PO4, NTU, and NO3, advanced wastewater treatment 
technologies (a combination of coagulation (FeCl3) and adsorption (Activated 
Carbon (AC))) are attractive. Considering that water reclamation can help 
provide an irrigation system for crops and domestic purified water, removing 
organic matter and nutrients prior to wastewater reuse is fundamental. In order 
to remove contaminants like organic matter and nutrients from wastewater, 
advanced wastewater treatment processes are recommended. The purpose of this 
paper is to investigate various doses of AC and FeCl3 in wastewater treatment 
and study the optimum conditions for the removal of COD, TSS, PO4, NTU, and NO3. 
Furthermore, the evaluated FeCl3'/AC's optimum functioning pH ranges from 6.5 to 
8.0, and their optimum working times range from 2.5 to 5.5 h. The optimum 
concentrations of AC were 0.1-25 g/L and 0.1-5 g/L of FeCl3. The most 
significant COD elimination rate (98%), the highest TSS elimination efficiency 
(94%), NTU elimination performance (99%), PO4 elimination (99%), and NO3 
elimination (67%), among the investigated FeCl3 and AC. Secondly, the effects of 
operational variables such as AC, FeCl3, time, and solution pH were modeled, 
optimized, and evaluated using response surface techniques based on the 
D-Optimal design. Input from the response surface approach findings was used to 
develop an artificial neural network-based prediction model and Non-dominated 
Sorting Genetic Algorithm II (NSGA-II).

Copyright © 2023 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.jenvman.2023.119429
PMID: 39491942

Conflict of interest statement: Declaration of competing interest The authors 
declare that they have no known competing financial interests or personal 
relationships that could have appeared to influence the work reported in this 
paper.


2. Vet Anim Sci. 2024 Mar 1;25:100332. doi: 10.1016/j.vas.2023.100332.
eCollection  2024 Sep.

Porcine skeletal muscle typing in histochemical and in-situ RT-PCR analysis.

Lin T(1)(2)(3)(4), Liu Z(1)(2)(3), Dai F(1)(2)(3), Wang H(5), Zuo J(3).

Author information:
(1)College of Life Science, Leshan Normal University, Sichuan, 61400, China.
(2)Key Laboratory of Bamboo Pest Control and Resource Development, Leshan, 
Sichuan 641000, People's Republic of China.
(3)South China Agricultural University, Guangdong, 510000, China.
(4)Guang'an Academy of Agriculture and Forestry Sciences, China.
(5)Guang'an Xinnong Development Co., Ltd, Guang'an, 638000, China.

Currently, there are plenty of histochemical methods to classify pig muscle 
fibers, which confused the naming and classification of muscle fibers. This 
study aims to analyze the difference and correlation of 6 different 
histochemical methods and select the most suitable method for muscle fiber 
classification at the molecular and histomological levels by in-situ RT-PCR and 
enzyme histochemical methods. Muscle fiber samples, including psoas (PM), 
semitendinosus (SM) and trapezius muscle (TM), were collected from Large Spotted 
(LS), Lantang (LT) and Landrace (LR) pigs at their market-ages (LS at 150 d, LT 
at 210 d, and LR at 150 d). 6 kinds of histochemical methods combining 
actomyosin adenosine triphosphatase (AM-ATPase) with succinate dehydrogenase 
(SDH) enzyme were conducted to differentiate fiber types. 2 types of fibers (I 
and II) were differentiated by acid 2-fibre (2-AC) or alkaline 2-fibre 
classification(2-AL), 3 types of fibers (βR, αR and αW) by 3-AC or 3-AL, and 4 
types of fibers (I, IIa, IIx and IIb) by 4-AC, or 4-AL. Results showed that AC 
and AL muscle-fiber classification were consistent in reflecting the 
characteristics of muscle fibers(P > 0.05), but the color of each muscle fiber 
type was just opposite. AC methods may be superior to AL methods because of 
their clear staining background, the sensitivity to staining condition. But 
there were breed differences and tissue specificity in the optimal preincubation 
condition. The optimal acid preincubation condition for classifying muscle 
fibers was pH4.30 for LT, while pH 4.35 for the LS and LR pigs. Meanwhile the 
optimal acid preincubation condition was pH4.35 for PM, while pH4.40 for TM or 
SM. For further selection from 2, 3, 4-AC, in-situ RT-PCR was applied to detect 
the mRNA distribution of myosin heavy chain I (MyHC-I). By combining in-situ PCR 
with enzyme histochemistry methods, MyHC-I gene and its product - Type I 
fibrocytes were directly located in cells at both molecular level and 
morphological level. Compared with the cross-sectional area (CSA) of different 
muscle fibers (i.e. I, II, βR, αR, αW, IIa, IIx and IIb) identified by enzyme 
histochemistry, it was found that the CSAs with stronger mRNA expression signal 
of MyHC-Ⅰ were closer to those of the Type I muscle fiber measured by 4-AC 
enzyme histochemistry (P > 0.05). Therefore, 4-AC may be considered as the most 
proper muscle typing method to study muscle fiber typing as well as meat 
quality. And the combination of in-situ RT-PCR and histochemistry may help 
better understand porcine muscle fiber characteristics and meat quality in pigs.

© 2024 The Author(s).

DOI: 10.1016/j.vas.2023.100332
PMCID: PMC11225689
PMID: 38975272

Conflict of interest statement: We certify that there is no conflict of interest 
with any financial organization regarding the material discussed in the 
manuscript.


3. Molecules. 2024 Jan 15;29(2):420. doi: 10.3390/molecules29020420.

Urchin-like Ce(HCOO)(3) Synthesized by a Microwave-Assisted Method and Its 
Application in an Asymmetric Supercapacitor.

He Q(1), Wang W(2), Li G(3), Chen W(2), Yang X(1), Ni C(1), Fang X(1).

Author information:
(1)Key Laboratory of Air-Driven Equipment Technology of Zhejiang Province, 
Quzhou University, Quzhou 324000, China.
(2)Department of Mechanical Engineering, Zhejiang University of Technology, 
Hangzhou 310058, China.
(3)R&D Department, Quzhou Hixee Electronic Technology Co., Ltd., Quzhou 324000, 
China.

In this work, a series of urchin-like Ce(HCOO)3 nanoclusters were synthesized 
via a facile and scalable microwave-assisted method by varying the irradiation 
time, and the structure-property relationship was investigated. The optimization 
of the reaction time was performed based on structural characterizations and 
electrochemical performances, and the Ce(HCOO)3-210 s sample shows a specific 
capacitance as high as 132 F g-1 at a current density of 1 A g-1. This is due to 
the optimal mesoporous hierarchical structure and crystallinity that are 
beneficial to its conductivity, offering abundant Ce3+/Ce4+ active sites and 
facilitating the transportation of electrolyte ions. Moreover, an asymmetric 
supercapacitor based on Ce(HCOO)3//AC was fabricated, which delivers a maximum 
energy density of 14.78 Wh kg-1 and a considerably high power density of 15,168 
W kg-1. After 10,000 continuous charge-discharge cycles at 3 A g-1, the ASC 
device retains 81.3% of its initial specific capacitance. The excellent 
comprehensive electrochemical performance of this urchin-like Ce(HCOO)3 offers 
significant promise for practical supercapacitor applications.

DOI: 10.3390/molecules29020420
PMCID: PMC10820376
PMID: 38257333

Conflict of interest statement: The authors declare that this study received 
funding from Quzhou Hixee Electronic Technology Co., Ltd. The funder was not 
involved in the study design, collection, analysis, interpretation of data, the 
writing of this article or the decision to submit it for publication.


4. Sci Rep. 2023 Sep 26;13(1):16100. doi: 10.1038/s41598-023-43309-1.

Effect of copper oxide (CuO) and vanadium oxide (V(2)O(5)) addition on the 
structural, optical and electrical properties of corundum (α-Al(2)O(3)).

Al-Mushaki MAA(1), Al-Ariki SA(2), Alnehia A(2).

Author information:
(1)Department of Physics, Faculty of Applied Science, Thamar University, 87246, 
Dhamar, Yemen. mohammedalmushki@gmail.com.
(2)Department of Physics, Faculty of Applied Science, Thamar University, 87246, 
Dhamar, Yemen.

In this work, we prepared a pure α-Al2O3, α-Al2O3/CuO (AC) and α-Al2O3/V2O5 (AV) 
nanocomposite. The sol-gel method was used to prepare pure α-Al2O3, (AC) and 
(AV) samples at 1200 °C. Structural, electrical, and optical properties of the 
prepared samples were investigated using the X-ray diffraction (XRD), UV-Visible 
spectrophotometer, and conductivity meter, respectively. The XRD results 
confirmed the crystalline nature and the presence of the hexagonal structure of 
α-Al2O3, the rhombohedra structure of CuAlO2 and the tetragonal structure of 
V2O5. Moreover, the crystallite size of pure α-Al2O3 was 43.1 nm, while the 
crystallite size of α-Al2O3 in samples AC and AV nanocompsite was 24.05 nm and 
34.84 nm respectively. The optical measurements showed that the band gap α-Al2O3 
decreased significantly from 5.28 eV for pure to 3.7 and 3.4 eV to AC and AV 
respectively. The DC electrical conductivity (σd.c) values were measured for all 
prepared samples at room temperature. The electrical conductivity was 2.4 × 10-7 
and 1.8 × 10-7 (Ω cm)-1 in AC and AV nanocompsite respectively, while ionic 
conductivity (σion) decreased from 3 × 10-10 in pure α-Al2O3 to 7 × 10-5 and 
1 × 10-5 in AC and AV nanocompsite, respectively. The results showed an 
improvement in the structural, optical, and electrical properties, which may 
make these materials a candidate for use in many applications, such as 
photocatalytic, gas sensors, optoelectronics, microelectronics, semiconductor 
devices, ……etc.

© 2023. Springer Nature Limited.

DOI: 10.1038/s41598-023-43309-1
PMCID: PMC10522612
PMID: 37752282

Conflict of interest statement: The authors declare no competing interests.


5. J Cancer Res Clin Oncol. 2023 Nov;149(15):13811-13821. doi: 
10.1007/s00432-023-05115-0. Epub 2023 Aug 3.

AML consolidation therapy: timing matters.

Reimann AM(1), Schalk E(2), Jost F(1)(3), Mougiakakos D(2), Weber D(4), Döhner 
H(4), Récher C(5), Dumas PY(6), Ditzhaus M(1), Fischer T(2), Sager S(7).

Author information:
(1)Department of Mathematics, Otto von Guericke University (OVGU), Magdeburg, 
Germany.
(2)Clinics of Hematology and Oncology, Otto von Guericke University (OVGU), 
Magdeburg, Germany.
(3)R&D, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany.
(4)Department of Internal Medicine III, University Hospital, Ulm, Germany.
(5)Service d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, 
Centre Hospitalier Universitaire, Toulouse, France.
(6)Service d'Hématologie Clinique et de Thérapie Cellulaire, Centre Hospitalier 
Universitaire de Bordeaux, Bordeaux, France.
(7)Department of Mathematics, Otto von Guericke University (OVGU), Magdeburg, 
Germany. sager@ovgu.de.

PURPOSE: Infections due to severe neutropenia are the most common 
therapy-associated causes of mortality in patients with acute myeloid leukemia 
(AML). New strategies to lessen the severity and duration of neutropenia are 
needed.
METHODS: Cytarabine is commonly used for AML consolidation therapy; we compared 
high- and intermediate-dose cytarabine administration on days 1, 2, and 3 
(AC-123) versus days 1, 3, and 5 (AC-135) in consolidation therapy of AML. 
Recently, clinical trials demonstrated that high-dose AC-123 resulted in a 
shortened white blood cell (WBC) recovery time compared with high-dose AC-135. 
Our main hypothesis is that this is also the case for different cytarabine 
dosage, granulocyte colony-stimulating factor (G-CSF) administration, and cycle 
lengths. We analyzed 334 treatment schedules on virtual cohorts of digital 
twins.
RESULTS: Comparison of 32,565 simulated consolidation cycles resulted in a 
reduction in the WBC recovery time for AC-123 in 99.6% of the considered cycles 
(median reduction 3.5 days) without an increase in the number of leukemic blasts 
(lower value in 94.2% of all cycles), compared to AC-135.
CONCLUSION: Our numerical study supports the use of AC-123 plus G-CSF as 
standard conventional AML consolidation therapy to reduce the risk for 
life-threatening infectious complications.

© 2023. The Author(s).

DOI: 10.1007/s00432-023-05115-0
PMCID: PMC10590325
PMID: 37535164

Conflict of interest statement: DM consults for Abbvie, Beigene, BMS, Gilead, 
Janssen, Novartis, and Takeda. HD consults Abbvie, Agios, Amgen, Astellas, 
AstraZeneca, Berlin-Chemie, Bristol Myers Squibb, Celgene, Daiichi Sankyo, 
GEMoaB, Gilead, Janssen, Jazz Pharmaceuticals, Novartis, Servier, Stemline, and 
Syndax. His institute has been receiving support from Abbvie, Agios, Amgen, 
Astellas, Bristol Myers Squibb, Jazz Pharmaceuticals, Kronos-Bio, Novartis, and 
Pfizer. CR is on the advisory boards of Abbvie, Astellas, BMS, Jazz Pharma, 
Novartis, Servier, and Takeda; his institution is supported by Abbvie, Astellas, 
BMS, Jazz Pharmaceuticals, and Iqvia. PYD consults for Daiichi-Sankyo, Jazz 
Pharmaceutical, Astellas, Abbvie, BMS, Janssen, and Novartis; his institution is 
supported by Astellas, Roche, Gilead, Daiichi-Sankyo, BMS, Servier, and 
Novartis. All other authors declare no competing interests.