Worldwide, there are plants known as psychoactive plants that naturally contain psychedelic active components. They have a high concentration of neuroprotective substances that can interact with the nervous system to produce psychedelic effects. Despite these plants' hazardous potential, recreational use of them is on the rise because of their psychoactive properties. Early neuroscience studies relied heavily on psychoactive plants and plant natural products (NPs), and both recreational and hazardous NPs have contributed significantly to the understanding of almost all neurotransmitter systems. Worldwide, there are many plants that contain psychoactive properties, and people have been using them for ages. Psychoactive plant compounds may significantly alter how people perceive the world.
1. Chem Biodivers. 2020 Jan;17(1):e1900504. doi: 10.1002/cbdv.201900504. Epub 2019 Dec 13. Composition and Intraspecific Chemical Variability of Leaf Essential Oil of Laggera pterodonta from Côte d'Ivoire. Kambiré DA(1), Brice Boti J(1), Yapi TA(1), Ouattara ZA(2), Paoli M(3), Bighelli A(3), Tomi F(3), Casanova J(3). Author information: (1)Laboratoire de Chimie Organique Biologique, UFR-SSMT, Université Félix Houphouët-Boigny-Abidjan, BP V34, Abidjan, Côte d'Ivoire. (2)Laboratoire de Chimie BioOrganique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 0801, Abidjan, Côte d'Ivoire. (3)Université de Corse-CNRS, UMR 6134 SPE, Équipe Chimie et Biomasse, Route des Sanguinaires, 20000, Ajaccio, France. The chemical composition of 44 leaf oil samples of Laggera pterodonta (DC.) Sch.Bip. ex Oliv. (Asteraceae) from Côte d'Ivoire was investigated, using combination of chromatographic (GC-FID) and spectroscopic (GC/MS, 13 C-NMR) techniques. Two oil samples chosen according to their chromatographic profiles were submitted to column chromatography and all fractions of CC were analyzed by GC-FID, GC/MS and 13 C-NMR. In total, 83 components accounting for 96.5 to 99.4 % of the whole chemical composition were identified. Significant variations were observed within terpene classes: monoterpene hydrocarbons (0.4-22.7 %), oxygenated monoterpenes (32.9-54.9 %), sesquiterpene hydrocarbons (18.6-38.3 %) and oxygenated sesquiterpenes (3.5-38.4 %). Thus, the 44 compositions were subjected to hierarchical cluster analysis (HCA) and principal component analysis (PCA). Two groups were differentiated according to their composition. All the samples contained 2,5-dimethoxy-p-cymene, α-humulene and (E)-β-caryophyllene among the main components. Other components were present at appreciable contents and allowed differentiation of two groups: sabinene and germacrene D for Group I; 10-epi-γ-eudesmol and eudesm-7(11)-en-4α-ol for Group II. All the samples collected in Eastern Côte d'Ivoire constituted Group I, while samples collected in the Central area of the country constituted Group II. © 2019 Wiley-VHCA AG, Zurich, Switzerland. DOI: 10.1002/cbdv.201900504 PMID: 31664789 [Indexed for MEDLINE]