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  Psychoactive Plant Database - Neuroactive Phytochemical Collection





Worldwide, there are plants known as psychoactive plants that naturally contain psychedelic active components. They have a high concentration of neuroprotective substances that can interact with the nervous system to produce psychedelic effects. Despite these plants' hazardous potential, recreational use of them is on the rise because of their psychoactive properties. Early neuroscience studies relied heavily on psychoactive plants and plant natural products (NPs), and both recreational and hazardous NPs have contributed significantly to the understanding of almost all neurotransmitter systems. Worldwide, there are many plants that contain psychoactive properties, and people have been using them for ages. Psychoactive plant compounds may significantly alter how people perceive the world.

 

Compound Summary

 

PLANT NAME:- Argyreia nervosa     PPD ID:- PPD-ID16_7


COMPOUND/COMMON NAME:- setoclavine; (+)-form, 8-epimer
CAS ID
478-93-3
INCHI KEY
BGVUWLLRNRBDAY-UHFFFAOYSA-N
MOLECULAR WEIGHT
254.33
MOLECULAR FORMULA
C16H18N2O
MOLECULAR MASS
254.333
BIOLOGICAL SOURCE
Argyreia nervosa
DATA SOURCE
Dictionary of Natural Product. http://dnp.chemnetbase.com. .; Borsutzky M, Passie T, Paetzold W, Emrich HM, Schneider U. Hawaiianische Holzrose: (Psycho-)Pharmakologische Wirkungen der Samen der Argyreia nervosa Eine fallbezogene Darstellung [Hawaiian baby woodrose: (Psycho-) Pharmacological effects of the seeds of Argyreia nervosa. A case-orientated demonstration]. Nervenarzt. 2002 Sep;73(9):892-6. German. doi: 10.1007/s00115-002-1374-4. PMID: 12215884.
CHEMICAL CLASS OF COMPOUND
Ergoline and derivatives
NLRP3 DOCKING SCORE(Kcal/mol)
-3.132
CANONICAL SMILES   CN1CC(C)(O)C=C2c3cccc4[nH]cc(c34)CC21
BIOACTIVITY REPORTED FOR NEURODEGENERATIVE DISEASES   Yes
SYNONYMS
(+)-Setoclavine, CHEBI:172496, L013893, 7,9-dimethyl-4,6,6a,8-tetrahydroindolo[4,3-g]quinolin-9-ol, 4,6-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaen-4-ol
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